Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909008 | 0.76 | MITF (0.37) | SMN1; SMN2MITFPER2LMNA | |
| SCHEMBL20553757 | 0.69 | LMNA (0.44) | SMN1; SMN2TP53HPGDMITFLMNA | |
| SCHEMBL27731773 | 0.66 | MITF (0.34) | SMN1; SMN2HPGDMITFPER2 | |
| SCHEMBL27648790 | 0.65 | MITF (0.36) | SMN1; SMN2HPGDMITFPER2 | |
| SCHEMBL6219776 | 0.64 | LMNA (0.50) | SMN1; SMN2TP53HPGDLMNACA12 | |
| SCHEMBL12084022 | 0.63 | LMNA (0.39) | SMN1; SMN2HPGDLMNA | |
| SCHEMBL7097178 | 0.62 | ALDH1A1 (0.39) | LMNA | |
| SCHEMBL27497087 | 0.62 | MITF (0.35) | SMN1; SMN2MITFLMNACA12CA1 | |
| SCHEMBL14495118 | 0.62 | CHRNB2 (0.39) | LMNA | |
| SCHEMBL2785830 | 0.61 | SMN1; SMN2 (0.45) | SMN1; SMN2TP53HPGDMITFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068824-A | Novel 3, 5-disubstituted-3H-imidazo [4,5-B ] pyridines and 3, 5-disubstituted-3H- [1,2,3] triazolo [4,5-B ] pyridine compounds as protein kinase modulators | INDIAN INCOZEN THERAPEUTICS PVT LTD | 2013-04-24 | — | — | CN | disclosed |