SCHEMBL27905

SCHEMBL27905

CCCCNc1cc(Cl)c(Nc2ccccc2)c2c1C(=O)OC21c2ccccc2Oc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP2C9 P11712 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
BRCA1 P38398 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP3A4 P08684 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
NR4A2 P43354 1/20 0.32
PGR P06401 1/20 0.32
KCNH3 Q9ULD8 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3970970 0.91 HPGD (0.38) KDM4ECYP2C9ALDH1A1HPGDALOX15
SCHEMBL548194 0.90 CYP2C9 (0.36) KDM4ERAB9ASMN1; SMN2CYP2C9ALDH1A1
SCHEMBL339448 0.87 TLR8 (0.36) KDM4ERAB9ASMN1; SMN2CYP2C9ALDH1A1
SCHEMBL16430376 0.81 ALDH1A1 (0.38) KDM4ERAB9ACYP2C9ALDH1A1HPGD
SCHEMBL9337785 0.80 ALDH1A1 (0.32) CYP2C9ALDH1A1HPGDALOX15ALOX12
SCHEMBL4084681 0.80 KDM4E (0.36) KDM4ERAB9ASMN1; SMN2CYP2C9ALDH1A1
SCHEMBL9565549 0.80 HPGD (0.38) CYP2C9ALDH1A1HPGDALOX15ALOX12
SCHEMBL4659426 0.79 ALOX15 (0.41) CYP2C9ALDH1A1HPGDALOX15ALOX12
SCHEMBL10951352 0.79 HSP90AA1 (0.39) KDM4ESMN1; SMN2CYP2C9ALDH1A1HPGD
SCHEMBL3977963 0.78 CYP3A4 (0.34) KDM4ERAB9ASMN1; SMN2CYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2404764-B1 HEAT-SENSITIVE RECORDING MATERIAL AND METHOD FOR PRODUCING SAME OJI HOLDINGS CORP (JP) 2016-04-20 EP disclosed
US-8513160-B2 Heat-sensitive recording material and method for producing same Oji Holdings Corporation (JP) 2013-08-20 US disclosed
EP-2404764-A1 HEAT-SENSITIVE RECORDING MATERIAL AND METHOD FOR PRODUCING SAME Oji Paper Co., Ltd. (JP) 2012-01-11 EP disclosed
US-20110318511-A1 HEAT-SENSITIVE RECORDING MATERIAL AND METHOD FOR PRODUCING SAME OJI PAPER CO., LTD. (JP) 2011-12-29 US disclosed