SCHEMBL4659426

SCHEMBL4659426

Nc1cc(Cl)c(Nc2ccccc2)c2c1C(=O)OC21c2ccccc2Oc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.41
HPGD P15428 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX12 P18054 1/20 0.41
BRCA1 P38398 1/20 0.41
HSD17B10 Q99714 1/20 0.41
FTO Q9C0B1 6/20 0.34
HTT P42858 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
SMAD3 P84022 2/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
KMT2A Q03164 1/20 0.34
PRMT1 Q99873 1/20 0.34
ACE2 Q9BYF1 1/20 0.34
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2185607 0.87 ALDH1A1 (0.41) ALOX15HPGDALDH1A1CYP2C9ALOX12
SCHEMBL3970970 0.82 HPGD (0.38) ALOX15HPGDALDH1A1CYP2C9ALOX12
SCHEMBL16430376 0.82 ALDH1A1 (0.38) ALOX15HPGDALDH1A1CYP2C9ALOX12
SCHEMBL27905 0.79 KDM4E (0.37) ALOX15HPGDALDH1A1CYP2C9ALOX12
SCHEMBL8753889 0.78 FTO (0.40) ALOX15HPGDALDH1A1CYP2C9ALOX12
SCHEMBL10606910 0.78 FTO (0.40) ALOX15HPGDALDH1A1CYP2C9ALOX12
SCHEMBL6537056 0.75 HPGD (0.40) ALOX15HPGDALDH1A1CYP2C9ALOX12
SCHEMBL10885589 0.75 HPGD (0.40) ALOX15HPGDALDH1A1CYP2C9ALOX12
SCHEMBL10910338 0.74 GRK6 (0.37) ALOX15HPGDALDH1A1CYP2C9ALOX12
SCHEMBL4667092 0.74 CYP2C9 (0.39) ALOX15HPGDALDH1A1CYP2C9ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1685972-B1 THERMAL RECORDING SHEET AND THERMAL RECORDING SHEET PACK OJI PAPER CO (JP) 2008-12-17 EP disclosed
EP-1685972-A1 THERMAL RECORDING SHEET AND THERMAL RECORDING SHEET PACK Oji Paper Co., Ltd. (JP) 2006-08-02 EP disclosed