Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27923629 | 0.83 | CYP1A2 (0.35) | L3MBTL1TDP1KMT2AMEN1CYP1A2 | |
| SCHEMBL27905683 | 0.82 | SLC6A2 (0.36) | L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL27923627 | 0.79 | KCNA3 (0.34) | TDP1ALDH1A1RECQL | |
| SCHEMBL27905695 | 0.77 | SLC6A2 (0.35) | KMT2AMEN1CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL27905680 | 0.77 | NPC1 (0.36) | — | |
| SCHEMBL27905697 | 0.74 | PPARD (0.39) | ALDH1A1 | |
| SCHEMBL27923626 | 0.71 | LMNA (0.40) | KDM4EKMT2AMEN1CYP2D6 | |
| SCHEMBL27905687 | 0.71 | L3MBTL1 (0.41) | L3MBTL1KDM4EKMT2AALDH1A1GAA | |
| SCHEMBL6233331 | 0.71 | SLC6A2 (0.39) | L3MBTL1TDP1KDM4EKMT2AMEN1 | |
| SCHEMBL3326060 | 0.67 | IDO1 (0.48) | L3MBTL1TDP1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097333-A | Spirocyclically substituted 1,3-propane dioxide derivatives, methods for the production thereof and use of the same as medicament | SANOFI SA | 2013-05-08 | — | — | CN | disclosed |