Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905687 | 0.86 | L3MBTL1 (0.41) | DRD2MAOBGRM2ALDH1A1AOC3 | |
| SCHEMBL27923629 | 0.85 | CYP1A2 (0.35) | DRD2MAOBDRD1DRD3ALDH1A1 | |
| SCHEMBL27923627 | 0.84 | KCNA3 (0.34) | LTA4HGRM2ALDH1A1 | |
| SCHEMBL27905695 | 0.76 | SLC6A2 (0.35) | MAOBALDH1A1 | |
| SCHEMBL27905680 | 0.76 | NPC1 (0.36) | MAOBGRM2 | |
| SCHEMBL12083017 | 0.74 | PPARD (0.47) | PPARDDRD2MAOBLTA4HALDH1A1 | |
| SCHEMBL27905684 | 0.74 | L3MBTL1 (0.36) | ALDH1A1 | |
| SCHEMBL27923626 | 0.74 | LMNA (0.40) | DRD2 | |
| SCHEMBL5543276 | 0.74 | ALDH1A1 (0.40) | LTA4HALDH1A1 | |
| SCHEMBL2350595 | 0.70 | PPARD (0.45) | PPARDDRD2MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097333-A | Spirocyclically substituted 1,3-propane dioxide derivatives, methods for the production thereof and use of the same as medicament | SANOFI SA | 2013-05-08 | — | — | CN | disclosed |