Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PTPRF | P10586 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27906315 | 0.86 | SIGMAR1 (0.49) | BCHEBACE1CYP1A2 | |
| SCHEMBL27889799 | 0.82 | PYGL (0.49) | CYP2C19MMP2CYP1A2 | |
| SCHEMBL1096514 | 0.78 | CA2 (0.55) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23802828 | 0.77 | LMNA (0.58) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6540295 | 0.77 | LMNA (0.58) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4926907 | 0.77 | MEP1B (0.58) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4926892 | 0.77 | MEP1B (0.58) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2797012 | 0.77 | SIGMAR1 (0.68) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2451270 | 0.77 | SIGMAR1 (0.68) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2794528 | 0.77 | SIGMAR1 (0.68) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102906063-B | Prepare the method for Isoserine derivatives | INDENA S.P.A. (IT) | 2016-01-20 | — | — | CN | disclosed |
| CN-102906063-A | A process for the preparation of isoserine derivatives | INDENA SPA | 2013-01-30 | — | — | CN | disclosed |