SCHEMBL5875845

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5875752	0.82	ADORA3 (0.67)	CRHBPCRHR2ALDH1A1MEN1KMT2A
	SCHEMBL1062638	0.81	ADORA3 (0.69)	CRHBPCRHR2ALDH1A1MEN1KMT2A
	SCHEMBL5875686	0.81	ADORA3 (0.49)	ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
	SCHEMBL5875742	0.79	ADORA3 (0.47)	CRHBPCRHR2ALDH1A1MEN1KMT2A
	SCHEMBL17547304	0.78	ALDH1A1 (0.55)	CRHBPCRHR2ALDH1A1MEN1KMT2A
	SCHEMBL27908158	0.75	XDH (0.56)	ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
	SCHEMBL12793835	0.75	ALDH1A1 (0.64)	CRHBPCRHR2ALDH1A1MEN1KMT2A
	SCHEMBL3205770	0.72	TSHR (0.79)	ALDH1A1MEN1KMT2ASMN1; SMN2LMNA
	SCHEMBL5875593	0.72	CA1 (0.52)	KMT2AMAPTLMNA
	SCHEMBL19224557	0.69	LOXL2 (0.59)	ALDH1A1GAANPSR1ADORA3SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.