Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 4/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19972233 | 0.76 | MCL1 (0.43) | SLC6A3ALDH1A1PARP3NPSR1LMNA | |
| SCHEMBL19985883 | 0.76 | MCL1 (0.43) | SLC6A3ALDH1A1PARP3NPSR1LMNA | |
| SCHEMBL2792608 | 0.75 | MAOB (0.48) | SLC6A3PARP3LMNA | |
| SCHEMBL1901694 | 0.74 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2NPSR1SIGMAR1LMNA | |
| SCHEMBL1904591 | 0.74 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2NPSR1SIGMAR1LMNA | |
| SCHEMBL12525034 | 0.74 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2NPSR1SIGMAR1LMNA | |
| SCHEMBL28492624 | 0.73 | SLC9A1 (0.42) | SLC6A3ALDH1A1PARP3NPSR1SIGMAR1 | |
| SCHEMBL28490616 | 0.73 | MCL1 (0.49) | SLC6A3ALDH1A1PARP3SMN1; SMN2NPSR1 | |
| SCHEMBL1096906 | 0.73 | SLC6A4 (0.49) | SLC6A3TSHR | |
| SCHEMBL3150368 | 0.73 | MAPK1 (0.56) | ALDH1A1MTNR1APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100163070-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE | L'OREAL S.A. (FR) | 2010-07-01 | — | — | US | claimed |
| US-20190125051-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL (FR) | 2019-05-02 | — | — | US | disclosed |
| US-10092490-B2 | Method for straightening keratinous fibres using heating means and an amide | L'OREAL (FR) | 2018-10-09 | — | — | US | disclosed |
| US-20140326268-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL (FR) | 2014-11-06 | — | — | US | disclosed |
| US-8765107-B2 | Process for straightening keratin fibres with a heating means and denaturing agents | L'OREAL (FR) | 2014-07-01 | — | — | US | disclosed |
| US-20120192888-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L 'Oréal S.A., (FR) | 2012-08-02 | — | — | US | disclosed |
| US-20100163070-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE | L'OREAL S.A. (FR) | 2010-07-01 | — | — | US | disclosed |
| US-20100028280-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL S.A. (FR) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120192888-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | KRT18, KRTCAP2, TUBB4A | SLC6A3 4883/4885ALDH1A1 2916/4885PARP3 2307/4885 |
| US-20100028280-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | KRT18, KRTCAP2, TUBB4A | SLC6A3 4883/4885ALDH1A1 2916/4885PARP3 2307/4885 |
| US-20190125051-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | KRT18, KRTCAP2, TUBB4A | SLC6A3 4883/4885ALDH1A1 2916/4885PARP3 2307/4885 |
| US-10092490-B2 | Method for straightening keratinous fibres using heating means and an amide | KRT18, TUBB3, KIF5C | SLC6A3 4750/4885ALDH1A1 2077/4885PARP3 1552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.