Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27892283 | 0.78 | SLC6A2 (0.41) | OPRM1ADRB1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9986948 | 0.77 | OPRM1 (0.43) | OPRM1OPRK1OPRL1ADRB1HTR6 | |
| SCHEMBL27909415 | 0.75 | MAPT (0.43) | OPRM1OPRK1OPRL1GAAMAPT | |
| SCHEMBL12069837 | 0.71 | SLC6A4 (0.38) | OPRM1OPRK1OPRL1ADRB1HTR6 | |
| SCHEMBL23609411 | 0.69 | HTR6 (0.56) | OPRM1OPRK1OPRL1ADRB1HTR6 | |
| SCHEMBL30099664 | 0.69 | HTR6 (0.56) | OPRM1OPRK1OPRL1ADRB1HTR6 | |
| SCHEMBL27892286 | 0.68 | OPRM1 (0.41) | OPRM1MAPTSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10119880 | 0.67 | SLC6A4 (0.49) | OPRM1OPRK1ADRB1HTR6SLC6A4 | |
| SCHEMBL27735267 | 0.67 | DRD2 (0.38) | OPRM1OPRK1HTR6MAPTSLC6A4 | |
| SCHEMBL27836228 | 0.64 | DAO (0.46) | OPRM1OPRK1OPRL1ADRB1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947275-A | Piperidinyl-substituted 1, 3-dihydro-benzimidazol-2-ylideneamine derivatives | NOVARTIS AG | 2013-02-27 | — | — | CN | disclosed |