Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Methyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.78 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.78 |
| ▸ | ACHE | P22303 | 10/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL27837349 | 0.97 | APOBEC3A (0.82) | APOBEC3AAPOBEC3GACHETDP1KDM4E | |
| Water SCHEMBL35582 | 0.94 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHETDP1KDM4E | |
| Phosphine SCHEMBL27465237 | 0.91 | APOBEC3A (0.82) | APOBEC3AAPOBEC3GACHETDP1KDM4E | |
| Water SCHEMBL28744902 | 0.91 | APOBEC3A (0.82) | APOBEC3AAPOBEC3GACHETDP1KDM4E | |
| SCHEMBL12020269 | 0.91 | APOBEC3A (0.93) | APOBEC3AAPOBEC3GACHETDP1KDM4E | |
| SCHEMBL147815 | 0.91 | APOBEC3A (0.93) | APOBEC3AAPOBEC3GACHETDP1KDM4E | |
| Water SCHEMBL27482461 | 0.88 | APOBEC3A (0.78) | APOBEC3AAPOBEC3GACHETDP1KDM4E | |
| SCHEMBL7546898 | 0.88 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHETDP1KDM4E | |
| SCHEMBL7546894 | 0.88 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHETDP1KDM4E | |
| Hydrochloric Acid SCHEMBL237898 | 0.88 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHETDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103254131-A | Refining technology for dextromethorphan bulk medicine | SUZHOU GULI BIOTECHNOLOGY CO | 2013-08-21 | — | — | CN | claimed |
| CN-117551096-A | Preparation method of ionic 4-hydroxy-1, 5-naphthyridine europium complex | 苏州睿尔思科技有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-103254131-A | Refining technology for dextromethorphan bulk medicine | SUZHOU GULI BIOTECHNOLOGY CO | 2013-08-21 | — | — | CN | disclosed |
| CN-103254131-A | Refining technology for dextromethorphan bulk medicine | SUZHOU GULI BIOTECHNOLOGY CO | 2013-08-21 | — | — | CN | disclosed |
| CN-103073495-A | Preparation method for ent-3-methoxy-morphinan | Suzhou lixin pharmaceutical co ltd | 2013-05-01 | — | — | CN | disclosed |