Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.59 |
| ▸ | HTR7 | P34969 | 10/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907549 | 0.85 | CTSL (0.61) | HTR1AHTR7ALDH1A1LMNA | |
| SCHEMBL27917822 | 0.84 | HTT (0.62) | HTR1AHTR7HDAC8SFRP1STS | |
| SCHEMBL27900131 | 0.81 | FBP1 (0.57) | HTR1AHTR7DRD2HTR6HDAC8 | |
| SCHEMBL27772044 | 0.81 | ALDH1A1 (0.57) | HTR1AHTR7DRD2HTR6HDAC8 | |
| SCHEMBL14834140 | 0.80 | MGLL (0.57) | HTR1AHTR7DRD2HTR6HTR2A | |
| SCHEMBL4737973 | 0.80 | HDAC8 (0.53) | HTR1AHTR7DRD2HDAC8SFRP1 | |
| SCHEMBL2097769 | 0.80 | KMT2A (0.65) | HTR7DRD2HTR6HTR2ASFRP1 | |
| SCHEMBL16825813 | 0.79 | SIGMAR1 (0.49) | HTR1AHTR7ALDH1A1LMNAHTT | |
| SCHEMBL3806249 | 0.78 | CTSK (0.65) | HTR1AHTR7ALDH1A1LMNA | |
| SCHEMBL4785389 | 0.77 | ALDH1A1 (0.51) | HTR1AHTR7SFRP1STSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |