Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 5/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27900247 | 0.85 | CNR2 (0.55) | TGFBR1HTR7ALDH1A1PKM | |
| SCHEMBL27917915 | 0.85 | MAPT (0.59) | TGFBR1HTR7ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL28805529 | 0.85 | CNR1 (0.48) | TGFBR1ADRA1AADRA1BALDH1A1PKM | |
| SCHEMBL27917787 | 0.84 | TGFBR1 (0.48) | TGFBR1ADRA1AADRA1BALDH1A1MEN1 | |
| SCHEMBL18686319 | 0.82 | MGLL (0.64) | TGFBR1ADRA1AADRA1BHTR7 | |
| SCHEMBL28802154 | 0.82 | ALDH1A1 (0.49) | TGFBR1ADRA1AADRA1BALDH1A1CYP2C9 | |
| SCHEMBL27917806 | 0.82 | ALDH1A1 (0.52) | TGFBR1ADRA1AADRA1BALDH1A1MEN1 | |
| SCHEMBL5164880 | 0.81 | PI4KB (0.53) | ADRA1AADRA1BHTR7ALDH1A1MEN1 | |
| SCHEMBL5167099 | 0.81 | PI4KB (0.53) | ADRA1AADRA1BHTR7ALDH1A1MEN1 | |
| SCHEMBL27917809 | 0.80 | NPY5R (0.58) | ALDH1A1NSD2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |