Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29126251 | 0.88 | AR (0.44) | ARPGRHSD17B1HSD17B2PNMT | |
| SCHEMBL22472191 | 0.86 | HSP90AA1 (0.42) | ARPGRPNMTAPPHTR7 | |
| SCHEMBL30944692 | 0.86 | HSP90AA1 (0.42) | ARPGRPNMTAPPHTR7 | |
| SCHEMBL28760155 | 0.84 | AR (0.41) | ARPGRPNMTACHENPC1 | |
| SCHEMBL28858429 | 0.83 | ACHE (0.42) | ARPGRPNMTACHEHTR7 | |
| SCHEMBL29126249 | 0.83 | KDM4E (0.41) | ARPGRHSD17B1HSD17B2PNMT | |
| SCHEMBL21295458 | 0.82 | APP (0.58) | PNMTAPPHTR7HTR2BNPC1 | |
| SCHEMBL29126292 | 0.82 | HTR1A (0.46) | ARPGRPNMTHTR7 | |
| SCHEMBL17574468 | 0.81 | PRKAB2 (0.49) | HSD17B1HSD17B2PNMTAPPHTR7 | |
| SCHEMBL27949993 | 0.80 | KCNH2 (0.39) | PNMTAPPNPC1RAB9ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102617382-B | 2-amino-fluorene containing ester group and preparation method thereof | UNIV HARBIN ENG | 2014-01-29 | — | — | CN | disclosed |
| CN-103086851-A | Thermosetting resin monomer containing fluorene and benzocyclobutene construction unit as well as preparation method and application thereof | SHANGHAI INST ORGANIC CHEM | 2013-05-08 | — | — | CN | disclosed |