SCHEMBL28760155

SCHEMBL28760155

Fc1ccc(-c2cccc3c2Cc2ccccc2-3)cc1C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AR P10275 8/20 0.41
MPL P40238 3/20 0.39
PGR P06401 2/20 0.39
PNMT P11086 1/20 0.39
ACHE P22303 1/20 0.38
GPR3 P46089 1/20 0.36
CHRM3 P20309 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
SCN9A Q15858 1/20 0.35
ALOX5AP P20292 1/20 0.34
FEN1 P39748 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27919002 0.84 AR (0.47) ARPGRPNMTACHENPC1
SCHEMBL28858429 0.84 ACHE (0.42) ARPGRPNMTACHENPC1
SCHEMBL28860542 0.79 PNMT (0.44) PNMTACHENPC1RAB9AALOX5AP
SCHEMBL29126251 0.79 AR (0.44) ARPGRPNMTACHENPC1
SCHEMBL27863670 0.77 KIF11 (0.46) PNMTNPC1RAB9ASCN9A
SCHEMBL17574468 0.77 PRKAB2 (0.49) PNMTNPC1RAB9A
SCHEMBL18335236 0.77 PNMT (0.44) PNMTACHENPC1RAB9AALOX5AP
SCHEMBL27942181 0.76 PNMT (0.49) ARPNMTACHENPC1RAB9A
SCHEMBL28851607 0.76 PNMT (0.52) PNMTNPC1RAB9A
SCHEMBL28451614 0.75 HTR7 (0.49) PNMTACHENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100489057-C Blue polyarylether high molecule electroluminescent material and its preparation method CHANGCHUN APPLIED CHEMISTRY (CN) 2009-05-20 CN disclosed
CN-1800296-A Blue polyarylether high molecule electroluminescent material and its preparation method CHANGCHUN APPLIED CHEMISTRY (CN) 2006-07-12 CN disclosed