Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790553 | 1.00 | ROCK1 (0.32) | ROCK1ITGB3ITGA2BPPARAPDE2A | |
| SCHEMBL7889785 | 0.91 | L3MBTL1 (0.32) | ROCK1ITGB3ITGA2BPPARA | |
| SCHEMBL7900607 | 0.91 | L3MBTL1 (0.32) | ROCK1ITGB3ITGA2BPPARA | |
| SCHEMBL7902090 | 0.80 | USP30 (0.32) | ITGB3ITGA2B | |
| SCHEMBL2814040 | 0.79 | CNR2 (0.34) | ROCK1 | |
| SCHEMBL2814043 | 0.79 | CNR2 (0.34) | ROCK1 | |
| SCHEMBL2790483 | 0.79 | ALDH1A1 (0.31) | — | |
| SCHEMBL2790479 | 0.79 | ALDH1A1 (0.31) | — | |
| SCHEMBL2790813 | 0.78 | PROKR1 (0.36) | ITGB3ITGA2B | |
| SCHEMBL2789916 | 0.77 | REN (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |