Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973307 | 0.86 | PKM (0.45) | PKMKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8973588 | 0.86 | PKM (0.45) | PKMKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL12319426 | 0.81 | EDNRA (0.52) | KMT2AMAPTHPGDNPC1MEN1 | |
| SCHEMBL9147014 | 0.80 | ALDH1A1 (0.41) | PKMKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL3053745 | 0.78 | PKM (0.67) | PKMKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8973923 | 0.77 | PKM (0.44) | PKMKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL13469238 | 0.76 | PKM (0.50) | PKMKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL5078857 | 0.76 | TSHR (0.55) | PKMKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL9710339 | 0.76 | CA12 (0.52) | PKMKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL2531253 | 0.75 | LMNA (0.68) | KMT2AMEN1KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153300-A | Heteroaryls and uses thereof | MILLENNIUM PHARM INC | 2013-06-12 | — | — | CN | disclosed |