Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973162 | 0.88 | ALDH1A1 (0.42) | PKMALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL27923752 | 0.86 | PKM (0.46) | PKMALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8973588 | 0.84 | PKM (0.45) | PKMALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL388034 | 0.82 | MAPT (0.55) | MAPTKMT2AMEN1NPC1HPGD | |
| SCHEMBL9729949 | 0.81 | CYP3A4 (0.44) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL9147014 | 0.79 | ALDH1A1 (0.41) | PKMALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL240151 | 0.77 | ALDH1A1 (0.49) | PKMALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL3053745 | 0.76 | PKM (0.67) | PKMALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4095819 | 0.76 | LMNA (0.44) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL8973923 | 0.76 | PKM (0.44) | PKMALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508441-A | Herbicidal substituted thienylsulphonylureas | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| US-5430006-A | Herbicidal substituted thienylsulphonylureas | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-04 | — | — | US | disclosed |
| EP-0590416-A1 | Substituted sulfonylureas as herbizides | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0224078-A1 | Thienyl sulfonyl guanidine derivatives | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |