Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | ADCY10 | Q96PN6 | 3/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PNP | P00491 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12268312 | 0.79 | ADCY10 (0.40) | TAAR1ADCY10HTR6MAOB | |
| SCHEMBL605971 | 0.74 | TAAR1 (0.49) | TAAR1ADCY10HTR6PIK3CDPIK3CB | |
| SCHEMBL2719810 | 0.73 | KDM4E (0.50) | TAAR1ADCY10HTR6PIK3CDPIK3CB | |
| SCHEMBL29167134 | 0.72 | HTR6 (0.64) | TAAR1ADCY10HTR6PIK3CDPIK3CB | |
| SCHEMBL605021 | 0.72 | HTR6 (0.62) | HTR6 | |
| SCHEMBL602263 | 0.71 | HRH4 (0.52) | ADCY10HTR6LMNA | |
| SCHEMBL244450 | 0.70 | — | — | |
| SCHEMBL29194643 | 0.69 | PIK3CD (0.41) | TAAR1ADCY10HTR6PIK3CDPIK3CB | |
| SCHEMBL9701516 | 0.69 | PNP (0.53) | TSHRPNPLMNA | |
| Iodide SCHEMBL21835041 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101668423-B | 2-aminopyrimidine modulators of the histamine H4 receptor | JANSSEN PHARMACEUTICA NV | 2013-10-30 | — | — | CN | claimed |