Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADCY10 | Q96PN6 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375889 | 0.77 | PIK3CD (0.39) | KDM4EALDH1A1HTR6PIK3CDPIK3CB | |
| SCHEMBL27923978 | 0.73 | TAAR1 (0.51) | HTR6PIK3CDPIK3CBTAAR1PNP | |
| SCHEMBL29194643 | 0.72 | PIK3CD (0.41) | KDM4EHTR6PIK3CDPIK3CBTAAR1 | |
| SCHEMBL3957456 | 0.72 | — | — | |
| SCHEMBL29167134 | 0.72 | HTR6 (0.64) | KDM4EHTR6PIK3CDPIK3CBTAAR1 | |
| SCHEMBL1494107 | 0.72 | AURKA (0.48) | GRM4HSP90AA1HRH4AURKAPRKACA | |
| SCHEMBL2752018 | 0.72 | SMN1; SMN2 (0.46) | KDM4EALDH1A1HTR6TAAR1TSHR | |
| SCHEMBL21241290 | 0.71 | ADRA1D (0.39) | KDM4EALDH1A1TAAR1TSHRLMNA | |
| SCHEMBL6920988 | 0.70 | L3MBTL1 (0.51) | ALDH1A1GRM4HSP90AA1TAAR1PNP | |
| SCHEMBL9539329 | 0.70 | PIK3CD (0.43) | KDM4EALDH1A1HTR6PIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635572-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012061698-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012061698-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-05-10 | — | — | WO | disclosed |