Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.60 |
| ▸ | MMP2 | P08253 | 4/20 | 0.57 |
| ▸ | MMP13 | P45452 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857836 | 0.90 | TLR7 (0.53) | MCL1MMP2MMP13NR4A2NR4A1 | |
| SCHEMBL22939882 | 0.85 | MMP13 (0.62) | MMP13TLR7 | |
| SCHEMBL29660311 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HPGDSTLR7PTPN1 | |
| SCHEMBL26319777 | 0.81 | MMP2 (0.52) | MCL1MMP2MMP13P4HTMHPGDS | |
| SCHEMBL7381559 | 0.81 | PTGER1 (0.61) | MCL1MMP2MMP13ALDH1A1HPGDS | |
| SCHEMBL26319518 | 0.81 | ALDH1A1 (0.73) | ALDH1A1HPGDSTLR7PTPN1 | |
| SCHEMBL352152 | 0.81 | HPGDS (0.73) | ALDH1A1HPGDSTLR7PTPN1 | |
| SCHEMBL4444241 | 0.80 | MMP13 (0.57) | MCL1MMP2MMP13P4HTMMMP1 | |
| SCHEMBL3568125 | 0.80 | MAPT (0.56) | MCL1MMP2MMP13HPGDSMMP1 | |
| Hydrochloric Acid SCHEMBL6821751 | 0.79 | HPGDS (0.71) | ALDH1A1HPGDSTLR7PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827839-A | 2‑（4‑（Benzyloxy）Phenyl）‑N‑（2‑（Piperidinyl-1 base）Ethyl）The formamide preparation method and applications of thiazole 4 | 淮海工学院 | 2018-03-23 | — | — | CN | claimed |
| CN-107827839-A | 2‑（4‑（Benzyloxy）Phenyl）‑N‑（2‑（Piperidinyl-1 base）Ethyl）The formamide preparation method and applications of thiazole 4 | 淮海工学院 | 2018-03-23 | — | — | CN | disclosed |
| CN-103097367-A | Phenylpropionic acid compound, preparation method therefor and medicinal use thereof | INST PHARM & TOXICOLOGY AMMS | 2013-05-08 | — | — | CN | disclosed |