Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359079 | 0.81 | GSK3B (0.44) | ALDH1A1LMNASMN1; SMN2SIGMAR1 | |
| SCHEMBL31571120 | 0.74 | ALDH1A1 (0.37) | ALDH1A1HPGDHTTTSHRSMN1; SMN2 | |
| SCHEMBL9305366 | 0.74 | ALDH1A1 (0.37) | ALDH1A1HPGDHTTTSHRSMN1; SMN2 | |
| SCHEMBL6936002 | 0.69 | BCHE (0.41) | ALDH1A1LMNASMN1; SMN2SIGMAR1 | |
| SCHEMBL9358633 | 0.69 | HRH3 (0.39) | RAB9AALDH1A1SIGMAR1MAPT | |
| SCHEMBL5256493 | 0.66 | EHMT2 (0.38) | ALDH1A1SMN1; SMN2SIGMAR1MAPTTDP1 | |
| SCHEMBL5259661 | 0.65 | MAOA (0.35) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11035453 | 0.65 | TSHR (0.39) | KDM4EALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL6933782 | 0.65 | LMNA (0.45) | KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL31571121 | 0.64 | MAOA (0.43) | RAB9AALDH1A1TSHRSMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103145643-B | Aminothiazole compound dehydration and alkylation method | UNIV WENZHOU | 2015-04-15 | — | — | CN | disclosed |
| CN-103145643-A | Aminothiazole compound dehydration and alkylation method | UNIV WENZHOU | 2013-06-12 | — | — | CN | disclosed |