Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 15/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122725 | 0.84 | GHSR (0.55) | GHSR | |
| SCHEMBL27927685 | 0.79 | GHSR (0.68) | GHSRALDH1A1TP53MAPT | |
| SCHEMBL124753 | 0.66 | GHSR (0.73) | GHSR | |
| SCHEMBL122760 | 0.65 | GHSR (0.80) | GHSR | |
| SCHEMBL124058 | 0.64 | GHSR (0.80) | GHSR | |
| SCHEMBL122516 | 0.63 | GHSR (0.84) | GHSR | |
| SCHEMBL122833 | 0.63 | GHSR (1.00) | GHSR | |
| SCHEMBL1762873 | 0.62 | HSD11B1 (0.37) | — | |
| SCHEMBL22057850 | 0.61 | SMN1; SMN2 (0.36) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27927691 | 0.61 | ALDH1A1 (0.45) | GHSRALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103443076-A | Indol-2-one derivatives disubstituted in position 3, their preparation and their therapeutic application | SANOFI AVENTIS | 2013-12-11 | — | — | CN | claimed |
| CN-103443076-A | Indol-2-one derivatives disubstituted in position 3, their preparation and their therapeutic application | SANOFI AVENTIS | 2013-12-11 | — | — | CN | disclosed |