Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | HPGD | P15428 | 9/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11732285 | 0.81 | L3MBTL1 (0.55) | KDM4ERXFP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11733370 | 0.81 | KDM4E (0.71) | KDM4ERXFP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27911647 | 0.80 | CASP3 (0.56) | KDM4EALDH1A1HPGDLMNARAB9A | |
| SCHEMBL11734827 | 0.79 | ADORA3 (0.59) | KDM4ERXFP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL17943818 | 0.75 | KDM4E (0.62) | KDM4ERXFP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL311250 | 0.74 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL17940142 | 0.74 | CYP3A4 (0.68) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL27911689 | 0.73 | SLC26A4 (0.54) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL6827283 | 0.73 | CA12 (0.47) | KDM4ERXFP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL17943841 | 0.72 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214506-B | Cumarone or aphthofurans derivative and preparation method thereof | SHANGHAI UNIVERSITY (CN) | 2016-02-17 | — | — | CN | disclosed |
| CN-103214506-A | Benzofuran or naphthofuran derivative and preparation method thereof | UNIV SHANGHAI | 2013-07-24 | — | — | CN | disclosed |