SCHEMBL311250

SCHEMBL311250

CC(=O)c1c(-c2ccccc2)oc2ccccc2c1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.62
KMT2A Q03164 5/20 0.62
MEN1 O00255 4/20 0.62
LMNA P02545 3/20 0.62
CA12 O43570 3/20 0.62
CA9 Q16790 3/20 0.62
CYP3A4 P08684 3/20 0.62
TP53 P04637 2/20 0.62
ALOX15 P16050 2/20 0.62
MAPK1 P28482 2/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
ABCB1 P08183 1/20 0.62
CALM1 P0DP23 1/20 0.62
AR P10275 1/20 0.62
PKM P14618 1/20 0.62
CYP1B1 Q16678 1/20 0.62
ABCG2 Q9UNQ0 1/20 0.59
ALDH1A1 P00352 7/20 0.58
HTT P42858 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11732285 0.89 L3MBTL1 (0.55) KDM4EKMT2AMEN1LMNACA12
SCHEMBL6527669 0.87 ALDH1A1 (0.69) KDM4EKMT2AMEN1LMNACA12
SCHEMBL9873754 0.84 KDM4E (0.62) KDM4EKMT2AMEN1LMNACA12
SCHEMBL26031862 0.84 KMT2A (0.62) KDM4EKMT2AMEN1LMNACA12
SCHEMBL27784285 0.84 KMT2A (0.63) KDM4EKMT2AMEN1LMNACA12
SCHEMBL23216981 0.82 KDM4E (0.56) KDM4EKMT2AMEN1LMNACA12
SCHEMBL1923200 0.82 KDM4E (0.59) KDM4EKMT2AMEN1LMNACA12
SCHEMBL27913159 0.82 KMT2A (0.59) KDM4EKMT2AMEN1LMNACA12
SCHEMBL1666929 0.81 CA12 (0.49) KDM4EKMT2AMEN1LMNACA12
SCHEMBL15328698 0.81 CA12 (0.52) KDM4EKMT2AMEN1LMNACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119770481-B NR4A1 transcriptional activity inhibitor and application thereof 浙江省肿瘤医院 2025-06-13 CN claimed
CN-106307378-A Soup cooking base flavoring and preparation method thereof 黔西南州万家绿宇康源保健品开发有限公司 2017-01-11 CN disclosed
EP-2314295-B1 Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices RESVERLOGIX INC (CA) 2015-01-28 EP disclosed
US-8410109-B2 Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices RESVERLOGIX CORP. (CA) 2013-04-02 US disclosed
US-8242130-B2 Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases RESVERLOGIX CORP. (CA) 2012-08-14 US disclosed
EP-1838296-B1 FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES RESVERLOGIX CORP (CA) 2012-08-08 EP disclosed
US-8093273-B2 Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases RESVERLOGIX CORP. (CA) 2012-01-10 US disclosed
EP-2332527-A2 Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases RESVERLOGIX CORP. (CA) 2011-06-15 EP disclosed
EP-2314295-A1 Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices Resverlogix, Inc (CA) 2011-04-27 EP disclosed
US-20090259048-A1 FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES RESVERLOGIX CORP. (CA) 2009-10-15 US disclosed
US-20090029987-A1 Pharmaceutical Compositions for the Prevention and Treatment of Complex Diseases and Their Delivery by Insertable Medical Devices RESVERLOGIX CORP. (CA) 2009-01-29 US disclosed
EP-1909788-A2 PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES RESVERLOGIX CORP. (CA) 2008-04-16 EP disclosed
EP-1838296-A2 FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES RESVERLOGIX CORP. (CA) 2007-10-03 EP disclosed
WO-2007016525-A2 PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES RESVERLOGIX CORP. (CA) 2007-02-08 WO disclosed
US-20060205767-A1 Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases HEPALINK (HONG KONG) LIMITED (HK) 2006-09-14 US disclosed
WO-2006045096-A2 FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES RESVERLOGIX CORP. (CA) 2006-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060205767-A1 Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases APOB, APOL1, FABP3 KDM4E 3504/4885KMT2A 2842/4885MEN1 4653/4885
US-20090259048-A1 FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES APOB, APOL1, FABP3 KDM4E 3504/4885KMT2A 2842/4885MEN1 4653/4885
US-20090029987-A1 Pharmaceutical Compositions for the Prevention and Treatment of Complex Diseases and Their Delivery by Insertable Medical Devices VCAM1, ICAM1, TGFB1 KDM4E 2334/4885KMT2A 3207/4885MEN1 3477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.