Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 8/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | SLC40A1 | Q9NP59 | 12/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.65 |
| ▸ | NFKBIA | P25963 | 3/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.65 |
| ▸ | G6PD | P11413 | 1/20 | 0.65 |
| ▸ | METAP2 | P50579 | 1/20 | 0.65 |
| ▸ | METAP1 | P53582 | 1/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | RELA | Q04206 | 2/20 | 0.62 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941063 | 0.83 | GLO1 (1.00) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL6862410 | 0.83 | GLO1 (1.00) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL27214286 | 0.81 | SLC40A1 (0.72) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL1507919 | 0.80 | SLC40A1 (0.76) | GLO1SLC40A1TDP1NFKBIAAGTR1 | |
| SCHEMBL30854809 | 0.80 | SLC40A1 (0.76) | GLO1SLC40A1TDP1NFKBIAAGTR1 | |
| SCHEMBL7190797 | 0.79 | GLO1 (0.65) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL442367 | 0.79 | SLC40A1 (1.00) | GLO1HTTSLC40A1TDP1NFKBIA | |
| SCHEMBL30925538 | 0.79 | TDP1 (0.73) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL29799662 | 0.79 | TDP1 (1.00) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL30925552 | 0.79 | SLC40A1 (0.78) | GLO1SLC40A1TDP1NFKBIAAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492028-B | Sulfonaminoquinoline hepcidin antagonists | 维福（国际）股份公司 | 2017-02-08 | — | — | CN | disclosed |
| CN-103492028-A | Novel sulfonaminoquinoline hepcidin antagonists | VIFOR INT AG | 2014-01-01 | — | — | CN | disclosed |