Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 7/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | SLC40A1 | Q9NP59 | 13/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.65 |
| ▸ | G6PD | P11413 | 1/20 | 0.65 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.65 |
| ▸ | METAP2 | P50579 | 1/20 | 0.65 |
| ▸ | METAP1 | P53582 | 1/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941063 | 1.00 | GLO1 (1.00) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL27930201 | 0.83 | GLO1 (0.71) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL13485950 | 0.82 | SLC40A1 (0.80) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL27214286 | 0.81 | SLC40A1 (0.72) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL22764962 | 0.81 | GLO1 (0.66) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL1507919 | 0.80 | SLC40A1 (0.76) | GLO1SLC40A1TDP1AGTR1G6PD | |
| SCHEMBL30854809 | 0.80 | SLC40A1 (0.76) | GLO1SLC40A1TDP1AGTR1G6PD | |
| SCHEMBL11997128 | 0.80 | SLC40A1 (0.82) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL13485953 | 0.80 | TDP1 (0.73) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL30925525 | 0.80 | SLC40A1 (0.80) | GLO1HTTALOX15SLC40A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691949-B2 | Quinoline sulfonamide compounds and their use as antibacterial agents | OTAGO INNOVATION LIMITED (NZ) | 2023-07-04 | — | — | US | disclosed |
| US-11213701-B2 | Neuroprotective quinoline sulfonamides | DAHL RUSSELL (US) | 2022-01-04 | — | — | US | disclosed |
| US-11213701-B2 | Neuroprotective quinoline sulfonamides | DAHL RUSSELL (US) | 2022-01-04 | — | — | US | disclosed |
| WO-2021146082-A1 | BIHETEROCYCLIC INHIBITORS OF ISPF FOR TREATMENT OF MICROBIAL INFECTIONS | POINT LOMA NAZARENE UNIVERSITY (US) | 2021-07-22 | — | — | WO | disclosed |
| EP-3708169-A1 | 2,3-DIHYDROBENZO[B][1,4]DIOXINE-6-SULFONAMIDE DERIVATIVES HAVING AN ANTICANCER ACTIVITY | Agios Pharmaceuticals, Inc. (US) | 2020-09-16 | — | — | EP | disclosed |
| US-20200188706-A1 | NEUROPROTECTIVE QUINOLINE SULFONAMIDES | DAHL RUSSELL (US) | 2020-06-18 | — | — | US | disclosed |
| US-20200188706-A1 | NEUROPROTECTIVE QUINOLINE SULFONAMIDES | DAHL RUSSELL (US) | 2020-06-18 | — | — | US | disclosed |
| US-8889638-B2 | Stimulus-triggered prodrugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-18 | — | — | US | disclosed |
| US-8889638-B2 | Stimulus-triggered prodrugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-18 | — | — | US | disclosed |
| US-8889638-B2 | Stimulus-triggered prodrugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-18 | — | — | US | disclosed |
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-22 | — | — | US | disclosed |
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-22 | — | — | US | disclosed |
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-22 | — | — | US | disclosed |
| US-20090179553-A1 | ELECTROLUMINESCENT MATERIAL CONTAINING AN ORGANIC LUMINESCENT SUBSTANCE | INSTITUT PROBLEM KHIMICESKON FIZKI ROSSIISKOI AKADEMII NAUK (IPKHF RAN) (RU) | 2009-07-16 | — | — | US | disclosed |
| US-20090179553-A1 | ELECTROLUMINESCENT MATERIAL CONTAINING AN ORGANIC LUMINESCENT SUBSTANCE | INSTITUT PROBLEM KHIMICESKON FIZKI ROSSIISKOI AKADEMII NAUK (IPKHF RAN) (RU) | 2009-07-16 | — | — | US | disclosed |
| US-20070240608-A1 | Black Ink Composition, Ink Set Containing the Same, and Ink Jet Recording Method | FUJIFILM CORPORATION (JP) | 2007-10-18 | — | — | US | disclosed |
| US-20070120920-A1 | Ink for inkjet, ink set for inkjet, and inkjet recording method | FUJIFILM CORPORATION (JP) | 2007-05-31 | — | — | US | disclosed |
| US-6790540-B2 | COMPLEX OF ZINC, ALUMINUM, COPPER, BERYLLIUM, RUTHENIUM, COBALT, RHODIUM, IRIDIUM OR PLATINUM WITH SULFONAMIDO-SUBSTITUTED AROMATIC COMPOUND; LIQUID CRYSTAL DISPLAYS | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20030138663-A1 | Organic electroluminescent element material and organic electroluminescent element | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2003-07-24 | — | — | US | disclosed |
| US-6528187-B1 | Luminescence element comprising pair of electrodes having formed therebetween plurality of organic compound thin film layers comprising electron-transporting layer which comprises specified compound | FUJI PHOTO FILM CO., LTD. (JP) | 2003-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200188706-A1 | NEUROPROTECTIVE QUINOLINE SULFONAMIDES | SUMO3, SUMO2, PSEN1 | GLO1 2894/4885HTT 111/4885ALOX15 3817/4885 |
| US-11213701-B2 | Neuroprotective quinoline sulfonamides | SUMO3, SUMO2, PSEN1 | GLO1 2894/4885HTT 111/4885ALOX15 3817/4885 |
| US-11691949-B2 | Quinoline sulfonamide compounds and their use as antibacterial agents | NQO2, SDHA, SIRT5 | GLO1 369/4885HTT 3885/4885ALOX15 4586/4885 |
| US-20030138663-A1 | Organic electroluminescent element material and organic electroluminescent element | ELAVL1, AGO2, ELAVL3 | GLO1 1934/4885HTT 4043/4885ALOX15 535/4885 |
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | PREP, ADAM10, DNPEP | GLO1 150/4885HTT 3890/4885ALOX15 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.