SCHEMBL7190797

SCHEMBL7190797

O=S(=O)(Nc1cccc2cccnc12)C(F)(F)F

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 4/20 0.65
HTT P42858 2/20 0.65
ALOX15 P16050 1/20 0.65
SLC40A1 Q9NP59 14/20 0.63
TDP1 Q9NUW8 4/20 0.60
AGTR1 P30556 2/20 0.60
G6PD P11413 1/20 0.60
NFKBIA P25963 1/20 0.60
METAP2 P50579 1/20 0.60
METAP1 P53582 1/20 0.60
PAX8 Q06710 1/20 0.60
ATM Q13315 1/20 0.60
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
MITF O75030 1/20 0.56
S1PR4 O95977 1/20 0.56
ALDH1A1 P00352 1/20 0.56
LMNA P02545 1/20 0.56
MAPT P10636 1/20 0.56
S1PR1 P21453 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3265300 0.79 CA2 (0.50)
SCHEMBL6862410 0.79 GLO1 (1.00) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL27930201 0.79 GLO1 (0.71) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL29941063 0.79 GLO1 (1.00) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL27214286 0.78 SLC40A1 (0.72) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL11335563 0.78 MEN1 (0.52) HTTKMT2AMEN1
SCHEMBL27214327 0.77 SLC40A1 (0.75) SLC40A1TDP1NFKBIAKMT2AMEN1
SCHEMBL11973253 0.77 SLC40A1 (1.00) GLO1HTTSLC40A1TDP1AGTR1
SCHEMBL30925559 0.77 SLC40A1 (0.75) SLC40A1TDP1NFKBIAKMT2AMEN1
SCHEMBL11973658 0.76 SLC40A1 (1.00) GLO1SLC40A1TDP1AGTR1G6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6528187-B1 Luminescence element comprising pair of electrodes having formed therebetween plurality of organic compound thin film layers comprising electron-transporting layer which comprises specified compound FUJI PHOTO FILM CO., LTD. (JP) 2003-03-04 US disclosed