Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | WNT1 | P04628 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27930054 | 0.92 | MKNK1 (0.35) | ERCC5FEN1USP30MKNK1WNT1 | |
| SCHEMBL27930088 | 0.91 | HDAC6 (0.34) | ERCC5FEN1WNT1GSK3BDYRK1A | |
| SCHEMBL27930087 | 0.88 | OPRM1 (0.37) | ERCC5FEN1USP30MKNK1 | |
| SCHEMBL28805064 | 0.84 | ERCC5 (0.33) | ERCC5FEN1DGAT1USP30UCHL1 | |
| SCHEMBL27930057 | 0.75 | HDAC6 (0.34) | ERCC5FEN1USP30WNT1GSK3B | |
| SCHEMBL27930077 | 0.73 | GSTO1 (0.40) | ERCC5FEN1USP30 | |
| SCHEMBL27930202 | 0.73 | OPRM1 (0.35) | ERCC5FEN1USP30MKNK1 | |
| SCHEMBL27930182 | 0.72 | XDH (0.44) | ERCC5FEN1 | |
| SCHEMBL27266272 | 0.61 | ALDH1A1 (0.40) | — | |
| SCHEMBL162335 | 0.61 | RAB9A (0.44) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103228633-A | Heterocyclic compounds as DGAT1 inhibitors | PIRAMAL LIFE SCIENCES LTD | 2013-07-31 | — | — | CN | disclosed |