Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NQO1 | P15559 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1800595 | 0.79 | CA1 (0.56) | CA1CA2MAPTKDM4ECYP3A4 | |
| SCHEMBL28143419 | 0.78 | KDM4E (0.56) | CA1CA2MAPTKDM4ECYP3A4 | |
| SCHEMBL28053823 | 0.75 | CA1 (0.51) | CA1CA2MAPTKDM4ECYP3A4 | |
| SCHEMBL19484976 | 0.75 | CYP1B1 (0.60) | CA1CA2MAPTKDM4ECYP3A4 | |
| SCHEMBL29466790 | 0.75 | MAOB (0.70) | CA1CA2KDM4ECYP3A4TP53 | |
| SCHEMBL28556802 | 0.75 | CA1 (0.51) | CA1CA2MAPTKDM4ECYP3A4 | |
| SCHEMBL669375 | 0.75 | MAOB (0.70) | CA1CA2KDM4ECYP3A4TP53 | |
| SCHEMBL18150087 | 0.74 | BRAF (0.53) | CA1CA2MAPTKDM4ECYP3A4 | |
| SCHEMBL15431517 | 0.73 | CA2 (0.43) | CA2MAPTKDM4ELMNAKMT2A | |
| SCHEMBL28844992 | 0.73 | CA12 (0.65) | CA1CA2MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103254236-A | Preparation method of 4-aryl coumarin-3-phosphonate derivatives | UNIV SOOCHOW | 2013-08-21 | — | — | CN | disclosed |