Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 4/20 | 0.51 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2674700 | 0.80 | FABP4 (0.58) | FABP4HNF4APRNPFABP3FABP5 | |
| SCHEMBL8895763 | 0.80 | FABP4 (0.68) | FABP4HNF4APRNPFABP3FABP5 | |
| SCHEMBL18104841 | 0.80 | NPC1 (0.43) | MEN1KMT2AF2RALDH1A1HPGD | |
| SCHEMBL27950189 | 0.77 | FABP4 (0.55) | FABP4HNF4APRNPKDM4EMAPT | |
| SCHEMBL28289664 | 0.73 | FABP4 (0.55) | FABP4FABP3FABP5MEN1KMT2A | |
| SCHEMBL9861790 | 0.73 | BCAT2 (0.57) | FABP4HNF4AFABP3FABP5MEN1 | |
| SCHEMBL8973903 | 0.71 | ALDH1A1 (0.55) | FABP4MEN1KMT2AKDM4EMAPT | |
| SCHEMBL28789332 | 0.70 | FABP4 (0.47) | FABP4HNF4APRNPMEN1KMT2A | |
| SCHEMBL28531054 | 0.69 | FABP4 (0.46) | FABP4HNF4APRNPMEN1KMT2A | |
| SCHEMBL17244263 | 0.69 | MAPT (0.50) | MEN1KMT2AKDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509009-A | 2-substituted-5-phenyl furan compound, and preparation method, pharmaceutical composition and application thereof | SHANGHAI INST MATERIA MEDICA | 2014-01-15 | — | — | CN | disclosed |