Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.55 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 5/20 | 0.45 |
| ▸ | IKBKB | O14920 | 2/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27214460 | 0.86 | BCAT2 (0.63) | FABP4BCAT2KEAP1NFE2L2METAP2 | |
| SCHEMBL8895763 | 0.85 | FABP4 (0.68) | FABP4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2674700 | 0.85 | FABP4 (0.58) | FABP4KDM4EALDH1A1MAPTHNF4A | |
| SCHEMBL27704997 | 0.82 | BCAT2 (0.59) | BCAT2KEAP1NFE2L2METAP2PARP1 | |
| SCHEMBL1898663 | 0.81 | KEAP1 (0.56) | FABP4BCAT2KEAP1NFE2L2METAP2 | |
| SCHEMBL4151580 | 0.80 | BCAT2 (0.59) | BCAT2KEAP1NFE2L2METAP2PARP1 | |
| SCHEMBL27704996 | 0.79 | KEAP1 (0.58) | BCAT2KEAP1NFE2L2METAP2PARP1 | |
| SCHEMBL29712321 | 0.79 | BCAT2 (0.55) | BCAT2KEAP1NFE2L2METAP2PARP1 | |
| SCHEMBL407835 | 0.79 | BCAT2 (0.55) | BCAT2KEAP1NFE2L2METAP2PARP1 | |
| SCHEMBL2025737 | 0.79 | BCAT2 (0.71) | FABP4BCAT2KEAP1NFE2L2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103553859-B | A kind of method being prepared aminated compounds intermediate by acid amides | DU YEHONG (CN) | 2015-09-16 | — | — | CN | disclosed |
| CN-103553859-A | Method for preparing amine compound midbody by utilizing amide | ZHU YEHONG | 2014-02-05 | — | — | CN | disclosed |