Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 9/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 8/20 | 0.38 |
| ▸ | TUBB | P07437 | 8/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28093164 | 0.80 | MAOB (0.40) | CYP3A4MAPTALOX15ALOX12MAOB | |
| SCHEMBL592705 | 0.79 | CYP3A4 (0.39) | CYP3A4MAPTTDP1ALDH1A1CA1 | |
| SCHEMBL931551 | 0.78 | TDP1 (0.38) | CYP3A4MAPTALOX15ALOX12MAOB | |
| SCHEMBL25182107 | 0.77 | EP300 (0.39) | CYP3A4MAPTALOX15ALOX12MAOB | |
| SCHEMBL15475102 | 0.77 | ALOX5 (0.39) | CYP3A4MAPTALOX15ALOX12MAOB | |
| SCHEMBL1969378 | 0.76 | ACHE (0.39) | CYP3A4MAPTTUBB1 | |
| SCHEMBL11358289 | 0.74 | POLB (0.39) | MAPTALOX15ALOX12TUBB1ALDH1A1 | |
| SCHEMBL28188574 | 0.74 | LMNA (0.36) | CYP3A4MAPTTUBB1MAPK1 | |
| SCHEMBL219318 | 0.74 | GAA (0.42) | MAPTALOX12TDP1ALDH1A1TP53 | |
| SCHEMBL28176258 | 0.74 | HTR2A (0.34) | CYP3A4MAPTTSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103539722-A | Aryl-substituted methyl-connected bis-indoleacetic acid derivative and preparation method and application thereof | UNIVISION PHARMACEUTICAL CO LTD | 2014-01-29 | — | — | CN | disclosed |