Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966208 | 0.80 | HTR2A (0.35) | HTR2AHTR2CHTR2BCYP3A4HTR1A | |
| SCHEMBL592705 | 0.79 | CYP3A4 (0.39) | CYP3A4CYP1A2TSHRACHEMAPT | |
| SCHEMBL29198830 | 0.77 | HTR2A (0.37) | HTR2AHTR2CHTR2BCYP3A4HTR1A | |
| SCHEMBL27829826 | 0.77 | — | — | |
| SCHEMBL1969378 | 0.76 | ACHE (0.39) | CYP3A4ACHELMNAMAPTCA9 | |
| SCHEMBL219318 | 0.74 | GAA (0.42) | TSHRACHEMAPT | |
| SCHEMBL11358289 | 0.74 | POLB (0.39) | HTR2AHTR2CHTR2BTSHRMAPT | |
| SCHEMBL28228224 | 0.74 | L3MBTL1 (0.43) | CYP3A4TSHRLMNAMAPT | |
| SCHEMBL28188574 | 0.74 | LMNA (0.36) | HTR2AHTR2CHTR2BCYP3A4ACHE | |
| SCHEMBL27934835 | 0.74 | CYP3A4 (0.41) | CYP3A4CYP1A2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107245444-A | A kind of thorugh biologic engineering method cultivates the equipment and its breeding method of medical strain | 徐州工程学院 | 2017-10-13 | — | — | CN | claimed |
| CN-107737103-B | A kind of intratumor injection liquid for treating rhabdomyosarcoma | 张欣 | 2018-09-04 | — | — | CN | disclosed |
| CN-107737103-A | A kind of intratumor injection liquid for being used to treat rhabdomyosarcoma | 张欣 | 2018-02-27 | — | — | CN | disclosed |
| CN-107245444-A | A kind of thorugh biologic engineering method cultivates the equipment and its breeding method of medical strain | 徐州工程学院 | 2017-10-13 | — | — | CN | disclosed |