Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568297 | 0.82 | NPC1 (0.44) | MAPTLTA4HNPC1RAB9A | |
| SCHEMBL20474481 | 0.79 | LAP3 (0.70) | LAP3ANPEPRNPEPDNPEPCYP3A4 | |
| SCHEMBL5227811 | 0.79 | LAP3 (0.70) | LAP3ANPEPRNPEPDNPEPCYP3A4 | |
| SCHEMBL8494993 | 0.79 | LAP3 (0.70) | LAP3ANPEPRNPEPDNPEPCYP3A4 | |
| SCHEMBL30051855 | 0.78 | SRR (0.45) | TSHRPKMTRPA1SRREPHX1 | |
| SCHEMBL5707491 | 0.78 | PSMB1 (0.47) | LAP3ANPEPRNPEPDNPEPLTA4H | |
| Hydrochloric Acid SCHEMBL3841335 | 0.77 | LAP3 (0.68) | LAP3ANPEPRNPEPDNPEPPKM | |
| Hydrochloric Acid SCHEMBL20474460 | 0.77 | LAP3 (0.68) | LAP3ANPEPRNPEPDNPEPPKM | |
| SCHEMBL29015305 | 0.77 | RECQL (0.50) | MMP8CYP3A4PKM | |
| SCHEMBL29015308 | 0.77 | RECQL (0.50) | MMP8CYP3A4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282043-B | Congenital agyria therapeutic agent | OSAKA CITY UNIVERSITY (JP) | 2015-09-30 | — | — | CN | disclosed |
| CN-103282043-A | Lissencephaly therapeutic agent | UNIV OSAKA CITY | 2013-09-04 | — | — | CN | disclosed |