Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 3/20 | 0.45 |
| ▸ | KMO | O15229 | 7/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lofemizole SCHEMBL35441 | 0.79 | ADORA3 (0.47) | IKBKBIDO1MAPTHTTLMNA | |
| Lofemizole SCHEMBL44549 | 0.78 | SMN1; SMN2 (0.47) | IKBKBIDO1MAPTHTTLMNA | |
| SCHEMBL4866745 | 0.75 | PIK3CD (0.43) | ALDH1A1NOTUM | |
| SCHEMBL22434856 | 0.75 | ADORA3 (0.50) | ALDH1A1MAPTHPGDHTTADORA3 | |
| SCHEMBL9005997 | 0.75 | GYS1 (0.46) | AHRKMOBRAFIDO1NPSR1 | |
| SCHEMBL11275115 | 0.75 | IDO1 (0.69) | KMOBRAFIDO1NPSR1MAPT | |
| SCHEMBL30480489 | 0.74 | KMO (0.43) | KMOBRAFIDO1NPSR1ALDH1A1 | |
| SCHEMBL19396824 | 0.73 | DYRK1A (0.43) | — | |
| SCHEMBL21428970 | 0.72 | MAPK14 (0.54) | MAPT | |
| SCHEMBL3141937 | 0.72 | ASIC3 (0.41) | ALDH1A1MAPTHPGDADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102144046-B | 2-benzyl-4-(3,4-dichlorophenyl)-5-methylimidazole compound | SHIKOKU CHEM | 2014-02-26 | — | — | CN | disclosed |