Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 3/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | AXL | P30530 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28567638 | 0.85 | AAK1 (0.38) | AAK1GSK3AGSK3BAXLHSD11B1 | |
| SCHEMBL27920535 | 0.84 | SLC22A6 (0.45) | SLC22A6AAK1MTNR1AMTNR1BSGK1 | |
| SCHEMBL27939090 | 0.82 | SLC22A6 (0.48) | SLC22A6MTNR1AMTNR1BSGK1AXL | |
| SCHEMBL28761614 | 0.82 | DYRK1A (0.44) | SLC22A6AAK1MTNR1AMTNR1BSGK1 | |
| SCHEMBL27939107 | 0.82 | ALDH1A1 (0.42) | SLC22A6AAK1MTNR1AMTNR1BCLK1 | |
| SCHEMBL17324699 | 0.80 | PIK3CA (0.46) | SGK1GSK3AGSK3BAXLHSD11B1 | |
| SCHEMBL23194615 | 0.75 | AAK1 (0.46) | AAK1GSK3AGSK3BFLT3CLK1 | |
| SCHEMBL30020999 | 0.75 | AXL (0.63) | SGK1AXL | |
| SCHEMBL9938142 | 0.75 | AXL (0.63) | SGK1AXL | |
| SCHEMBL2814713 | 0.73 | AXL (0.47) | SGK1GSK3AGSK3BAXLHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347874-A | Dimeric iap inhibitors | NOVARTIS AG | 2013-10-09 | — | — | CN | disclosed |