Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132620 | 0.83 | MAPT (0.59) | KMT2AMEN1MAPTNR1H4NPC1 | |
| SCHEMBL19244913 | 0.80 | MEN1 (0.66) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL28483238 | 0.80 | LMNA (0.47) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL30061028 | 0.79 | L3MBTL1 (0.49) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL2650448 | 0.79 | L3MBTL1 (0.49) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL1673203 | 0.79 | LMNA (0.50) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL6508869 | 0.79 | MEN1 (0.82) | KMT2AMEN1MAPTCLK1POLB | |
| SCHEMBL2666244 | 0.79 | MEN1 (0.59) | KMT2AMEN1MAPTCLK1POLB | |
| Methyl Alcohol SCHEMBL10573082 | 0.78 | LMNA (0.50) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL29786739 | 0.78 | RAB9A (0.50) | KMT2AMEN1MAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102369197-B | 6-(3-aza-bicyclo[3.1.0]hex-3-yl)-2-phenyl-pyrimidines used as ADP receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2013-11-06 | — | — | CN | disclosed |