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Methylamine

Methylamine

SCHEMBL27945366

CN.Cc1c(C2NCCO2)ccc2c1C(=O)NC2=O

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ HPGD P15428 2/20 0.34
▸ HSD17B10 Q99714 2/20 0.34
▸ MAPK10 P53779 1/20 0.34
▸ PARP1 P09874 2/20 0.33
▸ GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27945363 0.97 ALDH1A1 (0.35) ALDH1A1KDM4EHPGDHSD17B10MAPK10
SCHEMBL31485539 0.77 KDM4E (0.40) ALDH1A1KDM4EHPGDHSD17B10MAPK10
SCHEMBL27625802 0.77 DRD2 (0.39) —
SCHEMBL5171611 0.65 PARP1 (0.46) ALDH1A1KDM4EHPGDHSD17B10PARP1
SCHEMBL32680469 0.64 TDP2 (0.56) ALDH1A1KDM4EHPGDHSD17B10PARP1
SCHEMBL10962827 0.64 TDP2 (0.56) ALDH1A1KDM4EHPGDHSD17B10PARP1
SCHEMBL27815645 0.64 PARP1 (0.39) ALDH1A1KDM4EHPGDHSD17B10MAPK10
SCHEMBL28989737 0.63 KDM4E (0.44) ALDH1A1KDM4EHPGDHSD17B10MAPK10
Hydrochloric Acid SCHEMBL31218470 0.63 TDP2 (0.54) ALDH1A1KDM4EHPGDHSD17B10PARP1
SCHEMBL7380979 0.62 HTR2C (0.46) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103391927-A Novel preparation method of linezolid and novel intermediate thereof LEE PHARMA LTD 2013-11-13 — — CN claimed