Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748488 | 0.84 | MAPT (0.54) | MAPTALDH1A1LMNAKDM4ERAD52 | |
| SCHEMBL27826908 | 0.83 | MAOA (0.33) | MAPTALDH1A1NR1H2HTT | |
| SCHEMBL27599739 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNAGAAPOLBHTT | |
| SCHEMBL6846616 | 0.78 | MEN1 (0.47) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL27925831 | 0.77 | MAPT (0.44) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL27925828 | 0.76 | KCNQ2 (0.35) | MAPTALDH1A1LMNARAD52GAA | |
| SCHEMBL11300671 | 0.76 | MAPT (0.40) | MAPTALDH1A1LMNAKDM4ERAD52 | |
| SCHEMBL27615060 | 0.75 | GFER (0.54) | MAPTALDH1A1LMNAKDM4ERAD52 | |
| SCHEMBL27721028 | 0.75 | ADRA2C (0.53) | MAPTALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL27773156 | 0.75 | LMNA (0.43) | MAPTLMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103443102-A | Bicyclic carboxamide inhibitors of kinases | ABBVIE INC | 2013-12-11 | — | — | CN | disclosed |