Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950241 | 0.91 | MAPT (0.35) | PPARGPPARARORC | |
| SCHEMBL27936029 | 0.91 | RXRA (0.36) | PPARGRXRARXRBCCR9RORC | |
| SCHEMBL28947564 | 0.82 | RORC (0.39) | PPARGPPARARORCPPARD | |
| SCHEMBL12096889 | 0.81 | PPARG (0.50) | PPARGPPARARXRARXRBCCR9 | |
| SCHEMBL27884472 | 0.80 | PHGDH (0.39) | PPARGPPARARXRARXRBRORC | |
| SCHEMBL28807361 | 0.79 | PPARG (0.36) | PPARGPPARARORCPPARD | |
| SCHEMBL27867759 | 0.78 | ACLY (0.38) | PPARGPPARAPPARDPLA2G4A | |
| SCHEMBL27950245 | 0.78 | PPARG (0.35) | PPARGPPARARXRARXRBCCR9 | |
| SCHEMBL27950250 | 0.77 | RORC (0.36) | PPARGRORC | |
| SCHEMBL27867729 | 0.77 | ACLY (0.38) | PPARGPPARAPPARDPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103554006-A | Use of indole derivatives as nurr-1 activators for the application thereof as a medicament for the treatment of parkinson's disease | FOURNIER LAB SA | 2014-02-05 | — | — | CN | disclosed |