SCHEMBL27958461

SCHEMBL27958461

O=CNC(CCCCC1CCCCC1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 12/20 0.41
KDM5A P29375 3/20 0.40
PHF8 Q9UPP1 3/20 0.40
KDM2A Q9Y2K7 3/20 0.40
KDM4C Q9H3R0 2/20 0.40
KDM4A O75164 1/20 0.40
EPHX1 P07099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31688618 0.76 SIGMAR1 (0.43) CPB2KDM5APHF8KDM2AKDM4C
SCHEMBL31688611 0.76 SIGMAR1 (0.43) CPB2KDM5APHF8KDM2AKDM4C
SCHEMBL23740241 0.76 GSR (0.50) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL10073275 0.76 GSR (0.50) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL7868415 0.76 GSR (0.50) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL23833698 0.75 SIGMAR1 (0.48) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL31688951 0.74 CPB2 (0.41) CPB2KDM5APHF8KDM2AKDM4C
SCHEMBL3023049 0.74 GPR84 (0.46) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL30088758 0.74 NAAA (0.47) EPHX1
SCHEMBL22697049 0.72 NAAA (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103819364-B The One-step Synthesis method of N-hydrocarbon acyl group cyclic lactam derivative CENTRAL SOUTH UNIVERSITY (CN) 2015-12-02 CN disclosed
CN-103819364-A One-pot synthesis method of N-hydrocarbon acyl cyclic lactam derivative UNIV CENTRAL SOUTH 2014-05-28 CN disclosed