Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.71 |
| ▸ | TGM2 | P21980 | 4/20 | 0.71 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CASP9 | P55211 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506317 | 0.84 | TGM2 (1.00) | CES1TGM2LRRK2CASP3MAOA | |
| SCHEMBL134453 | 0.84 | TGM2 (1.00) | CES1TGM2LRRK2CASP3MAOA | |
| SCHEMBL1462357 | 0.82 | TGM2 (0.96) | CES1TGM2LRRK2CASP3MAOA | |
| Methane SCHEMBL27958656 | 0.82 | TGM2 (0.96) | CES1TGM2LRRK2CASP3MAOA | |
| Nitrogen SCHEMBL29155961 | 0.81 | TGM2 (0.92) | CES1TGM2LRRK2CASP3MAOA | |
| Isatin SCHEMBL4624064 | 0.78 | MAOA (0.67) | LRRK2CASP3MAOAMAOBCASP1 | |
| Acetamide SCHEMBL8705155 | 0.77 | TGM2 (0.77) | CES1TGM2LRRK2MAOAMAOB | |
| Isatin SCHEMBL4625841 | 0.76 | MAOA (0.69) | LRRK2CASP3MAOAMAOBCASP1 | |
| 5-Fluoroisatin SCHEMBL11132105 | 0.75 | CES1 (0.80) | CES1TGM2LRRK2MAOAMAOB | |
| Propionamide SCHEMBL8706214 | 0.73 | TGM2 (0.71) | CES1TGM2LRRK2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432388-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2008-06-18 | — | — | EP | claimed |
| EP-1432428-B1 | Agent for colouring fibres containing keratin | HENKEL KGAA (DE) | 2006-11-02 | — | — | EP | claimed |
| US-20050262647-A1 | Agent for dyeing fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-12-01 | — | — | US | claimed |
| US-20050262647-A1 | Agent for dyeing fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050262647-A1 | Agent for dyeing fibers containing keratin | KRT18, CKAP4, KRTCAP2 | CES1 2379/4885TGM2 1412/4885LRRK2 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.