Sulfaquinoxaline

Sulfaquinoxaline

SCHEMBL27961007

Nc1ccc(S(=O)(=O)Nc2cnc3ccccc3n2)cc1.[Zn]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.97
CYP2C9 P11712 3/20 0.97
ATIC P31939 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.58
KDM4E B2RXH2 4/20 0.57
ALDH1A1 P00352 4/20 0.57
KMT2A Q03164 9/20 0.56
MEN1 O00255 8/20 0.56
POLB P06746 2/20 0.54
HPGD P15428 1/20 0.53
HSD17B10 Q99714 1/20 0.53
CYP3A4 P08684 2/20 0.52
CASP6 P55212 1/20 0.52
AURKA O14965 1/20 0.51
DHFR P00374 1/20 0.51
TSHR P16473 1/20 0.51
HTR6 P50406 2/20 0.51
MAPT P10636 1/20 0.50
CYP2C19 P33261 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfaquinoxaline SCHEMBL93789 0.99 LMNA (1.00) LMNACYP2C9ATICSMN1; SMN2KDM4E
Sulfaquinoxaline SCHEMBL29391090 0.99 LMNA (1.00) LMNACYP2C9ATICSMN1; SMN2KDM4E
Sulfaquinoxaline SCHEMBL4435622 0.99 LMNA (1.00) LMNACYP2C9ATICSMN1; SMN2KDM4E
Sulfaquinoxaline SCHEMBL301314 0.97 LMNA (0.97) LMNACYP2C9ATICSMN1; SMN2KDM4E
Sulfaquinoxaline SCHEMBL27992255 0.91 LMNA (0.85) LMNACYP2C9ATICSMN1; SMN2KDM4E
SCHEMBL30517293 0.86 LMNA (0.78) LMNACYP2C9ATICKDM4EALDH1A1
SCHEMBL1414326 0.86 LMNA (0.78) LMNACYP2C9ATICKDM4EALDH1A1
SCHEMBL15256346 0.84 LMNA (0.74) LMNACYP2C9ATICSMN1; SMN2KDM4E
SCHEMBL9703345 0.81 LMNA (0.69) LMNACYP2C9ATICSMN1; SMN2KDM4E
Chlorsulfaquinoxaline SCHEMBL6375915 0.80 LMNA (0.68) LMNACYP2C9ATICSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116179116-A Noctilucent weather-resistant adhesive and preparation method thereof 李超 2023-05-30 CN claimed
CN-104152140-A Blue fluorescent material and preparation method thereof UNIV NINGBO 2014-11-19 CN claimed
CN-116179116-A Noctilucent weather-resistant adhesive and preparation method thereof 李超 2023-05-30 CN disclosed
CN-116179116-A Noctilucent weather-resistant adhesive and preparation method thereof 李超 2023-05-30 CN disclosed
CN-104152140-B A kind of blue fluorescent material and preparation method thereof NINGBO UNIVERSITY (CN) 2016-04-20 CN disclosed
CN-104119863-B A kind of green fluorescent material and preparation method thereof NINGBO UNIVERSITY (CN) 2015-09-09 CN disclosed
CN-104152140-A Blue fluorescent material and preparation method thereof UNIV NINGBO 2014-11-19 CN disclosed
CN-104152140-A Blue fluorescent material and preparation method thereof UNIV NINGBO 2014-11-19 CN disclosed
CN-104119863-A Green fluorescent material and preparation method thereof UNIV NINGBO 2014-10-29 CN disclosed