Sulfaquinoxaline

Sulfaquinoxaline

SCHEMBL301314

Nc1ccc(S(=O)(=O)Nc2cnc3ccccc3n2)cc1.[NaH]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.97
CYP2C9 P11712 3/20 0.97
ATIC P31939 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.58
KDM4E B2RXH2 4/20 0.57
ALDH1A1 P00352 4/20 0.57
KMT2A Q03164 9/20 0.56
MEN1 O00255 8/20 0.56
POLB P06746 2/20 0.54
HPGD P15428 1/20 0.53
HSD17B10 Q99714 1/20 0.53
CYP3A4 P08684 2/20 0.52
CASP6 P55212 1/20 0.52
AURKA O14965 1/20 0.51
DHFR P00374 1/20 0.51
TSHR P16473 1/20 0.51
HTR6 P50406 2/20 0.51
MAPT P10636 1/20 0.50
CYP2C19 P33261 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfaquinoxaline SCHEMBL93789 0.99 LMNA (1.00) LMNACYP2C9ATICSMN1; SMN2KDM4E
Sulfaquinoxaline SCHEMBL4435622 0.99 LMNA (1.00) LMNACYP2C9ATICSMN1; SMN2KDM4E
Sulfaquinoxaline SCHEMBL29391090 0.99 LMNA (1.00) LMNACYP2C9ATICSMN1; SMN2KDM4E
Sulfaquinoxaline SCHEMBL27961007 0.97 LMNA (0.97) LMNACYP2C9ATICSMN1; SMN2KDM4E
Sulfaquinoxaline SCHEMBL27992255 0.91 LMNA (0.85) LMNACYP2C9ATICSMN1; SMN2KDM4E
SCHEMBL1414326 0.86 LMNA (0.78) LMNACYP2C9ATICKDM4EALDH1A1
SCHEMBL30517293 0.86 LMNA (0.78) LMNACYP2C9ATICKDM4EALDH1A1
SCHEMBL15256346 0.84 LMNA (0.74) LMNACYP2C9ATICSMN1; SMN2KDM4E
SCHEMBL9703345 0.81 LMNA (0.69) LMNACYP2C9ATICSMN1; SMN2KDM4E
Chlorsulfaquinoxaline SCHEMBL6375915 0.80 LMNA (0.68) LMNACYP2C9ATICSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113615639-A Ecological under-forest breeding method for high-quality broilers 贵州省畜牧兽医研究所 2021-11-09 CN claimed
EP-3829640-A1 METHODS FOR INHIBITING MICROBE GROWTH McMaster University (CA) 2021-06-09 EP claimed
WO-2020024060-A1 METHODS FOR INHIBITING MICROBE GROWTH MCMASTER UNIVERSITY (CA) 2020-02-06 WO claimed
US-20190145960-A1 COMPOSITIONS, SYSTEMS AND METHODS FOR GENE EXPRESSION NOISE DRUG SCREENING AND USES THEREOF THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE 2019-05-16 US claimed
EP-3470536-A1 COMPOSITIONS, SYSTEMS AND METHODS FOR GENE EXPRESSION NOISE DRUG SCREENING AND USES THEREOF The J. David Gladstone Institutes (US) 2019-04-17 EP claimed
US-10184933-B2 Compositions, systems and methods for gene expression noise drug screening and uses thereof The J. David Gladstone Industries (US) 2019-01-22 US claimed
CN-104668577-B A kind of nickel micro-and nano-particles and preparation method thereof 宁波大学 2019-01-15 CN claimed
CN-207380059-U A kind of sulfamido quantitatively detects external member and kit 联合益康(北京)生物科技有限公司 2018-05-18 CN claimed
US-9549942-B2 Composition for preventing or treating degenerative brain diseases including compound downregulating expression of BACE1 proteins Research & Business Foundation Sungkyunkwan University (KR) 2017-01-24 US claimed
CN-105998036-A Compound sulfa-nitazoxanide soluble powder for pigs and poultry 洛阳市兽药厂 2016-10-12 CN claimed
US-20160245796-A1 COMPOSITIONS, SYSTEMS AND METHODS FOR GENE EXPRESSION NOISE DRUG SCREENING AND USES THEREOF THE J. DAVID GLADSTONE INSTITUTES (US) 2016-08-25 US claimed
EP-3052662-A1 COMPOSITIONS, SYSTEMS AND METHODS FOR GENE EXPRESSION NOISE DRUG SCREENING AND USES THEREOF The J. David Gladstone Institutes (US) 2016-08-10 EP claimed
CN-105038271-A Asphalt insect-proof and water-proof roll BENGBU NANZI INSTR CO LTD 2015-11-11 CN claimed
CN-104668577-A Nickel micro nanoparticle and preparation method thereof UNIV NINGBO 2015-06-03 CN claimed
WO-2015051035-A1 COMPOSITIONS, SYSTEMS AND METHODS FOR GENE EXPRESSION NOISE DRUG SCREENING AND USES THEREOF THE J. DAVID GLADSTONE INSTITUTES (US) 2015-04-09 WO claimed
CN-104109466-A Long-lasting type aluminum alloy surface treating agent SHARP EXHIBITION TONGLING TECHNOLOGY CO LTD 2014-10-22 CN claimed
CN-102846640-A New method for preventing coccidiosis of fowl WANG HONGTAO 2013-01-02 CN claimed
US-20100221245-A1 TOPICAL SKIN CARE COMPOSITION DERMADOCTOR, LLC 2010-09-02 US claimed
CN-101496810-A Soluble and stable composition of tilmicosin and sulfonamides TIANJIN RUIPU BIOLOGY TECHNOLO (CN) 2009-08-05 CN claimed
CN-1843364-A Pharmaceutical for preventing and treating coccidiosis, and its usage method ZHUANG XIAOFENG (CN) 2006-10-11 CN claimed