Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | ATIC | P31939 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.57 |
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | DHFR | P00374 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfaquinoxaline SCHEMBL93789 | 1.00 | LMNA (1.00) | LMNACYP2C9ATICSMN1; SMN2KDM4E | |
| Sulfaquinoxaline SCHEMBL29391090 | 1.00 | LMNA (1.00) | LMNACYP2C9ATICSMN1; SMN2KDM4E | |
| Sulfaquinoxaline SCHEMBL301314 | 0.99 | LMNA (0.97) | LMNACYP2C9ATICSMN1; SMN2KDM4E | |
| Sulfaquinoxaline SCHEMBL27961007 | 0.99 | LMNA (0.97) | LMNACYP2C9ATICSMN1; SMN2KDM4E | |
| Sulfaquinoxaline SCHEMBL27992255 | 0.92 | LMNA (0.85) | LMNACYP2C9ATICSMN1; SMN2KDM4E | |
| SCHEMBL30517293 | 0.88 | LMNA (0.78) | LMNACYP2C9ATICKDM4EALDH1A1 | |
| SCHEMBL1414326 | 0.88 | LMNA (0.78) | LMNACYP2C9ATICKDM4EALDH1A1 | |
| SCHEMBL15256346 | 0.85 | LMNA (0.74) | LMNACYP2C9ATICSMN1; SMN2KDM4E | |
| SCHEMBL9703345 | 0.82 | LMNA (0.69) | LMNACYP2C9ATICSMN1; SMN2KDM4E | |
| Chlorsulfaquinoxaline SCHEMBL6375915 | 0.81 | LMNA (0.68) | LMNACYP2C9ATICSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118661-A1 | METHOD AND DEVICE FOR THE DETERMINATION OF MINOR CELL POPULATIONS IN HETEROGENEOUS CELL POPULATIONS | Medion Diagnostics AG (CH) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008080544-A1 | METHOD AND DEVICE FOR THE DETERMINATION OF MINOR CELL POPULATIONS IN HETEROGENEOUS CELL POPULATIONS | MEDION DIAGNOSTICS AG (CH) | 2008-07-10 | — | — | WO | disclosed |