Sulfaquinoxaline

Sulfaquinoxaline

SCHEMBL93789

Nc1ccc(S(=O)(=O)Nc2cnc3ccccc3n2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
CYP2C9 P11712 2/20 1.00
ATIC P31939 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.60
KDM4E B2RXH2 4/20 0.58
ALDH1A1 P00352 3/20 0.58
KMT2A Q03164 10/20 0.57
MEN1 O00255 8/20 0.57
POLB P06746 2/20 0.55
HPGD P15428 1/20 0.54
HSD17B10 Q99714 1/20 0.54
CASP6 P55212 1/20 0.53
CYP3A4 P08684 1/20 0.53
AURKA O14965 1/20 0.53
DHFR P00374 1/20 0.53
TSHR P16473 1/20 0.53
HTR6 P50406 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfaquinoxaline SCHEMBL4435622 1.00 LMNA (1.00) LMNACYP2C9ATICSMN1; SMN2KDM4E
Sulfaquinoxaline SCHEMBL29391090 1.00 LMNA (1.00) LMNACYP2C9ATICSMN1; SMN2KDM4E
Sulfaquinoxaline SCHEMBL301314 0.99 LMNA (0.97) LMNACYP2C9ATICSMN1; SMN2KDM4E
Sulfaquinoxaline SCHEMBL27961007 0.99 LMNA (0.97) LMNACYP2C9ATICSMN1; SMN2KDM4E
Sulfaquinoxaline SCHEMBL27992255 0.92 LMNA (0.85) LMNACYP2C9ATICSMN1; SMN2KDM4E
SCHEMBL30517293 0.88 LMNA (0.78) LMNACYP2C9ATICKDM4EALDH1A1
SCHEMBL1414326 0.88 LMNA (0.78) LMNACYP2C9ATICKDM4EALDH1A1
SCHEMBL15256346 0.85 LMNA (0.74) LMNACYP2C9ATICSMN1; SMN2KDM4E
SCHEMBL9703345 0.82 LMNA (0.69) LMNACYP2C9ATICSMN1; SMN2KDM4E
Chlorsulfaquinoxaline SCHEMBL6375915 0.81 LMNA (0.68) LMNACYP2C9ATICSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3889 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630043-A1 IMMUNE-ACTIVATING COMPLEXES Dynamic Cell Therapies, Inc. (US) 2025-10-15 EP claimed
EP-4630446-A1 ENGINEERED SWITCHES FOR IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF Dynamic Cell Therapies, Inc. (US) 2025-10-15 EP claimed
US-20250282842-A1 DECOY-RESISTANT INTERLEUKIN 18 ARMORED CELLS AND RELATED METHODS Simcha IL-18, Inc. 2025-09-11 US claimed
CN-120195301-A Method and system for detecting various antibiotics in water based on artificial intelligence 广东中加检测技术股份有限公司 2025-06-24 CN claimed
CN-119936254-A Method for simultaneously screening 56 drug residues in animal-derived hot pot food materials based on high-resolution mass spectrometry technology 重庆市食品药品检验检测研究院 2025-05-06 CN claimed
EP-4536217-A1 CO-AGENTS AS THERAPY AGAINST ANAEROBIC PATHOGENS Fleurir Abx LLC (US) 2025-04-16 EP claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
CN-113156143-B Blood group irregular antibody specificity identification method and reagent thereof 山东威高输血技术装备有限公司 2025-04-01 CN claimed
CN-112689758-B Device and method for checking the effect of a drug on microorganisms 上海宜晟生物科技有限公司 2025-03-28 CN claimed
CN-115501273-B Application of traditional Chinese medicine compound effective extract in preparation of medicine for resisting eimeria tenella 广西大学 2025-03-25 CN claimed
EP-0572560-A1 USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY SHAPIRO, Howard, K. (US) 1993-12-08 EP claimed
EP-0215200-B1 USE OF SULFANILAMIDO QUINOXALINES IN THE TREATMENT OF NEOPLASTIC DISEASES MERCK & CO. INC. (US) 1992-09-09 EP claimed
WO-1992014456-A1 USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY SHAPIRO HOWARD K (US) 1992-09-03 WO claimed
CN-1013182-B ANTI-THEFT AND ANTI-ROBBERY ALARM CONTROLLER FOR WHOLE AUTOMOBILE ZHAO XIJING (CN) 1991-07-17 CN claimed
US-4599416-A Process for the preparation of aqueous solutions of potentiated sulfonamides HOFFMANN-LA ROCHE INC. (US) 1986-07-08 US claimed
US-4532245-A Pharmaceutical compositions HOFFMANN-LA ROCHE INC. (US) 1985-07-30 US claimed
US-4358436-A Blood typing tests and reagents ORTHO DIAGNOSTICS, INC. (US) 1982-11-09 US claimed
US-4315932-A AND SULFANILAMIDES BURROUGHS WELLCOME CO. (US) 1982-02-16 US claimed
EP-0022669-A1 Method and reagent for blood typing and method for preparing this reagent ORTHO DIAGNOSTIC SYSTEMS INC. (US) 1981-01-21 EP claimed
US-4094976-A ANTICOCCIDIAL CYCLICAMINO ETHANOLS AND ESTERS THEREOF MERCK & CO., INC. (US) 1978-06-13 US claimed