Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 4/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2797615 | 0.84 | CHRM1 (0.40) | TAAR1CHRM1LMNAMEN1ALB | |
| SCHEMBL2267642 | 0.84 | LMNA (0.44) | CHRM1LMNAMEN1ALBKMT2A | |
| SCHEMBL2117818 | 0.83 | CCKBR (0.55) | CHRM1LMNAMEN1ALBKMT2A | |
| SCHEMBL2270644 | 0.80 | DYRK1A (0.42) | CHRM1LMNAMEN1ALBKMT2A | |
| SCHEMBL2264526 | 0.75 | CHRM1 (0.44) | CHRM1LMNAMEN1ALBKMT2A | |
| SCHEMBL2268675 | 0.74 | MEN1 (0.43) | CHRM1LMNAMEN1ALBKMT2A | |
| SCHEMBL2117702 | 0.73 | OPRK1 (0.36) | LMNACCKBRINPPL1 | |
| SCHEMBL2119671 | 0.72 | CCKBR (0.57) | CHRM1LMNAMEN1ALBKMT2A | |
| SCHEMBL3233295 | 0.72 | CCKBR (0.43) | CHRM1LMNAMEN1ALBKMT2A | |
| SCHEMBL2117932 | 0.71 | CCKBR (0.55) | CHRM1LMNAMEN1ALBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010121164-A2 | 1,4-BENZODIAZEPINONE COMPOUNDS AND THEIR USE IN TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-10-21 | — | — | WO | disclosed |