Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL11841667 | 0.84 | LMNA (0.56) | LMNATSHRABCC4GAAPTGS1 | |
| Benzene SCHEMBL28078101 | 0.84 | LMNA (0.50) | LMNATSHRHTTALDH1A1MAPT | |
| Biphenyl SCHEMBL310004 | 0.81 | ALDH1A1 (0.53) | LMNATSHRABCC4GAAPTGS1 | |
| Biphenyl SCHEMBL1952613 | 0.81 | ALDH1A1 (0.60) | LMNATSHRABCC4GAAPTGS1 | |
| Biphenyl SCHEMBL335359 | 0.81 | ALDH1A1 (0.60) | LMNATSHRABCC4GAAPTGS1 | |
| Biphenyl SCHEMBL4593266 | 0.81 | ALDH1A1 (0.60) | LMNATSHRABCC4GAAPTGS1 | |
| Biphenyl SCHEMBL473288 | 0.81 | ALDH1A1 (0.60) | LMNATSHRABCC4GAAPTGS1 | |
| SCHEMBL3767845 | 0.81 | PTGS2 (0.50) | LMNATSHRABCC4GAAPTGS1 | |
| Biphenyl SCHEMBL5143620 | 0.78 | ALDH1A1 (0.56) | LMNATSHRABCC4GAAPTGS1 | |
| SCHEMBL11835945 | 0.76 | HPRT1 (0.49) | TSHRGAAHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103864750-A | Derivative of N-biphenyl dichloroacetamide as well as preparation method and applications thereof | UNIV TSINGHUA | 2014-06-18 | — | — | CN | disclosed |
| CN-103864750-A | Derivative of N-biphenyl dichloroacetamide as well as preparation method and applications thereof | UNIV TSINGHUA | 2014-06-18 | — | — | CN | disclosed |