Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL473288 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Biphenyl SCHEMBL5071211 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTTSHRL3MBTL1 | |
| Biphenyl SCHEMBL4593266 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Biphenyl SCHEMBL1952613 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Biphenyl SCHEMBL7062651 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTTSHRL3MBTL1 | |
| Biphenyl SCHEMBL3399859 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTTSHRL3MBTL1 | |
| Biphenyl SCHEMBL335359 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Biphenyl SCHEMBL5143620 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTTSHRCYP3A4 | |
| Biphenyl SCHEMBL27755857 | 0.84 | ALDH1A1 (0.75) | ALDH1A1MAPTCYP3A4HSD17B10TDP1 | |
| Biphenyl SCHEMBL2901532 | 0.82 | SMN1; SMN2 (0.61) | ALDH1A1LMNAMAPTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503441-B2 | Process for preparing diphenylureido-dihalokynurenic acids and tosylate addition salts thereof | LOHOCLA RESEARCH CORPORATION | 2025-12-23 | — | — | US | claimed |
| EP-4227297-A1 | PROCESS FOR PREPARING DIPHENYLUREIDO-DIHALOKYNURENIC ACIDS AND TOSYLATE ADDITION SALTS THEREOF | Lohocla Research Corporation (US) | 2023-08-16 | — | — | EP | claimed |
| US-20220162168-A1 | PROCESS FOR PREPARING DIPHENYLUREIDO-DIHALOKYNURENIC ACIDS AND TOSYLATE ADDITION SALTS THEREOF | LOHOCLA RESEARCH CORPORATION | 2022-05-26 | — | — | US | claimed |
| CN-103785130-A | Fire extinguishing composition containing carboxylic acid derivatives | XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY | 2014-05-14 | — | — | CN | claimed |
| US-6962930-B1 | Compounds, compositions and method suitable for amelioration of withdrawal syndromes and withdrawal-induced brain damage | LOHOCLA RESEARCH CORPORATION (US) | 2005-11-08 | — | — | US | claimed |
| EP-1011676-B1 | QUINOLINE-UREA DERIVATIVES FOR THE TREATMENT OF WITHDRAWAL SYNDROME AND WITHDRAWAL-INDUCED BRAIN DAMAGE | LOHOCLA RES CORP (US) | 2005-08-31 | — | — | EP | claimed |
| EP-1011676-A4 | COMPOUNDS, COMPOSITIONS AND METHOD SUITABLE FOR AMELIORATION OF WITHDRAWAL SYNDROMES AND WITHDRAWAL-INDUCED BRAIN DAMAGE | LOHOCLA RES CORP (US) | 2004-08-11 | — | — | EP | claimed |
| EP-1011676-A1 | COMPOUNDS, COMPOSITIONS AND METHOD SUITABLE FOR AMELIORATION OF WITHDRAWAL SYNDROMES AND WITHDRAWAL-INDUCED BRAIN DAMAGE | Lohocla Research Corporation (US) | 2000-06-28 | — | — | EP | claimed |
| WO-1998055125-A1 | COMPOUNDS, COMPOSITIONS AND METHOD SUITABLE FOR AMELIORATION OF WITHDRAWAL SYNDROMES AND WITHDRAWAL-INDUCED BRAIN DAMAGE | LOHOCLA RESEARCH CORPORATION (US) | 1998-12-10 | — | — | WO | claimed |
| US-12503441-B2 | Process for preparing diphenylureido-dihalokynurenic acids and tosylate addition salts thereof | LOHOCLA RESEARCH CORPORATION | 2025-12-23 | — | — | US | disclosed |
| EP-4227297-A1 | PROCESS FOR PREPARING DIPHENYLUREIDO-DIHALOKYNURENIC ACIDS AND TOSYLATE ADDITION SALTS THEREOF | Lohocla Research Corporation (US) | 2023-08-16 | — | — | EP | disclosed |
| EP-4013416-A1 | PROCESS FOR PREPARING 1,4-DIHYDRO-4-OXOQUINOLINE-2-CARBOXYLATES AND 4-AMINOQUINOLINE COMPOUNDS THEREFROM | Lohocla Research Corporation (US) | 2022-06-22 | — | — | EP | disclosed |
| US-20220162168-A1 | PROCESS FOR PREPARING DIPHENYLUREIDO-DIHALOKYNURENIC ACIDS AND TOSYLATE ADDITION SALTS THEREOF | LOHOCLA RESEARCH CORPORATION | 2022-05-26 | — | — | US | disclosed |
| CN-113698312-A | Synthetic method of aromatic amide alkene compound | 南京先进生物材料与过程装备研究院有限公司 | 2021-11-26 | — | — | CN | disclosed |
| EP-0124296-A1 | Thermographic system using naphthoylated leuco phenazine dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-11-07 | — | — | EP | disclosed |
| US-4454218-A | WITH UNSATURATED COMPOUND AND PHOTOINITIATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-12 | — | — | US | disclosed |
| EP-0103294-A1 | N-alkylindolylidene and N-alkylbenzothiazolylidene alkanones as sensitizers for photopolymer compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4192677-A | ELECTROGRAPHIC CHARGE TRANSFER COMPOUNDS | RICOH CO., LTD. (JP) | 1980-03-11 | — | — | US | disclosed |
| US-4141729-A | 1,3,4-Oxadiazole derivatives and electrophotographic plates containing same | RICOH COMPANY, LTD. (JP) | 1979-02-27 | — | — | US | disclosed |
| US-3932658-A | Composition and method for lower blood sugar containing N-[4-(β-<2-methoxy-5-chloro-benzamido>-ethyl)-benzenesulfonyl]-N'-cyclopentyl-urea | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162168-A1 | PROCESS FOR PREPARING DIPHENYLUREIDO-DIHALOKYNURENIC ACIDS AND TOSYLATE ADDITION SALTS THEREOF | KMO, KYNU, PAH | ALDH1A1 979/4885LMNA 1867/4885MAPT 3949/4885 |
| US-12503441-B2 | Process for preparing diphenylureido-dihalokynurenic acids and tosylate addition salts thereof | KMO, KYNU, PAH | ALDH1A1 979/4885LMNA 1867/4885MAPT 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.