Sugi Predict

Sugi Predict / Compounds / SCHEMBL27965327

SCHEMBL27965327

SCHEMBL27965327

CC(C)(C)C([SiH2]OC(CCCCc1ccccc1)C(N)=O)C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.41
▸ GRIK1 P39086 1/20 0.40
▸ ACE P12821 1/20 0.40
▸ PPARG P37231 1/20 0.40
▸ PPARA Q07869 1/20 0.40
▸ FAAH O00519 1/20 0.39
▸ TRPA1 O75762 1/20 0.39
▸ POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28198431 0.78 NAAA (0.39) TRPA1
SCHEMBL1667087 0.77 FAAH (0.44) LMNAGRIK1PPARGPPARAFAAH
SCHEMBL2163274 0.76 FAAH (0.46) LMNAFAAHTRPA1
SCHEMBL27868012 0.74 FAAH (0.36) FAAH
SCHEMBL3928178 0.71 LTB4R (0.52) LMNAFAAHTRPA1
SCHEMBL9211958 0.70 FOLH1 (0.53) LMNAGRIK1FAAHTRPA1
SCHEMBL5514990 0.69 PPARG (0.54) PPARGPPARAFAAHTRPA1
SCHEMBL16673066 0.69 FAAH (0.49) FAAHPOLB
SCHEMBL5580783 0.68 KMT2A (0.48) LMNAPPARGPPARA
SCHEMBL865266 0.68 FAAH (0.58) LMNAGRIK1FAAHTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104892542-A ANTI INFLAMMATORY 2-OXOTHIAZOLES AND 2 -OXOOXAZOLES AVEXXIN AS 2015-09-09 — — CN disclosed
CN-103772312-A ANTI INFLAMMATORY 2-OXOTHIAZOLES AND 2 -OXOOXAZOLES AVEXXIN AS 2014-05-07 — — CN disclosed